Amoxicillin Dosage For Kids – Uses, Side Effects & Precautions

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“Antibiotics? No, my God, I won’t use them!”

This is the fear we have developed for antibiotics, especially if they are to be used for our children. The drugs, which were hitherto used generously, are now being replaced by alternative therapies to avoid any future complications.

In such a scenario, what would happen if your child’s doctor has prescribed amoxicillin for her? Before we administer medicine to our kids, it is good to have a general idea of the drug, its uses, side effects, and other details.

In this post, MomJunction will discuss this popular antibiotic called amoxicillin, its indication, usage, dosage, side-effects and more. Scroll down to learn about this drug.

What Is Amoxicillin?

Amoxicillin is a penicillin antibiotic used for treating bacterial infections including strep throat, skin infections, pneumonia, sinusitis, bronchitis, urinary tract infections and middle ear infections (1). However, this medicine is not recommended for treating any viral infections such as flu or cold (2).

The World Health Organisation has listed amoxicillin as the most effective and safe medicine for children. It is available as capsules, chewable tablets, tablets, and oral suspensions, and is usually given three times a day in eight-hour intervals or as prescribed by a doctor (3).

Amoxicillin is available in the US market under the brand name Amoxil, Amoxicot, Moxatag, Trimox, DisperMox, and Moxilin.

[ Read: Is Painkillers Safe For Children ]

When Is Amoxicillin Prescribed For Your Child?

Amoxicillin is prescribed for the below ailments:

  • Whooping cough or pneumonia
  • Worsened sinus infection
  • Prolonged cough of more than 14 days
  • A recurrent fever of 102° F
  • Yellow-green nasal discharge
  • Lower respiratory throat infection (lung infection)
  • Otitis media (ear infection)
  • E.coli-induced UTI
  • Amoxicillin dosage for strep throat in children is decided based on the result of a throat culture and rapid strep test.

The antibiotic is also used for:

  • Severe malnutrition in children (4).
  • Stomach ulcers caused by H.pyroli infection (used in combination with another antibiotic clarithromycin) (5).
  • Stomach acids (used in combination with lansoprazole) (6).
  • Pneumonia in infants (in combination with gentamycin) (7).

As the medicine is available in various forms, which one is the best for your child? Or what would the doctor prescribe?

How To Use/ Not Use Amoxicillin For Children?

Here is how you can take the drug in various forms:

  • When taking as a capsule, it should be swallowed with a glass of milk, juice or water.
  • When taking as an oral suspension, dilute the medicine with milk or water using a dosing syringe or a special dose-measuring spoon or a medicine cup. For infants and babies, you can mix the medicine with breastmilk or formula and place it directly on the tongue.
  • When taking as a chewable tablet, ask your child to chew the tablet well before swallowing.
  • When taking ER tablets, do not chew or crush the tablet but swallow with water or milk.

The antibiotic needs to be taken as per the instructions on the label or as told by your doctor. It can be taken with or without food.

There are a few more things for you to make a note of:

  • The drug interacts with over-the-counter and prescription medicines, vitamins and herbal products. So, if your child is taking any of these medicines, inform your physician about it before he prescribes amoxicillin. (Scroll down for the list)
Tell the doctor if your child is allergic to penicillin so that he does not prescribe amoxicillin.
  • Make a note of the medicines, foods, preservatives, dyes, and animals to which your child is allergic, and share it with the doctor.
  • Amoxicillin can cause serious allergies in kids. One such allergic reaction is called anaphylaxis (8). It is associated with symptoms like tightness or swelling of throat and difficulty in breathing. Your child might look pale and floppy. This condition needs immediate medical attention.
  • If your child has any kidney issues, asthma, hay fever, hives, or phenylketonuria, then your doctor should know about it.

[ Read: Throat Cancer In Children ]

Here is a list of drugs that amoxicillin interacts with and is commonly avoided together:

  1. Chlortetracycline
  2. Demeclocycline
  3. Cholera vaccine, live
  4. Lymecycline
  5. Doxycycline
  6. Methotrexate
  7. Meclocycline
  8. Minocycline
  9.  Methacycline
  10. Rolitetracycline
  11. Oxytetracycline
  12. Venlafaxine
  13. Warfarin
  14. Tetracycline

However, some combinations do work well for treating certain diseases. In such cases, the doctor can alter the dosage to make the best use of both the medicines.
Now that you know the ‘ifs and buts’ of amoxicillin, let’s see a few of its features.

Characteristics Of Amoxicillin

  • The antibiotic is easily absorbed by the gastrointestinal tract. It gets diffused into the body fluids and tissues, except into the brain and spinal fluids.
  • It is a narrow microbiologic spectrum antibiotic (9), which targets specific gram positive or gram negative bacteria.
  • Amoxicillin comes in good flavor and you don’t need to run behind your kids to give this medicine.

Amoxicillin should be given in the right amount, no less and no more than what is recommended.

[ Read: Benadryl For Kids ]

Amoxicillin Dosage Chart Based On The Child’s Weight/ Age

The dosage could vary depending on the condition and its severity. Given below is the list of recommended amoxicillin dosages for kids:

1. Ear/nose/throat infection (10)

Mild/Moderate infection doseSevere infection
Children ≥ 40 kg500mg twice daily


250mg thrice daily

875mg twice daily


250mg thrice daily

Children > 3 months and less than 40kg 25mg/kg/day every 12 hours


20mg/kg/day every 8 hours

45mg/kg/day every 12 hours


40mg/kg/day every 8 hours

2. Skin/skin structure infection

Mild/Moderate infection doseSevere infection
Children ≥ 40kg500mg twice daily


250mg thrice daily

875mg twice daily


250mg thrice daily

Children > 3 months and less than 40kg25mg/kg/day every 12 hours


20mg/kg/day every 8 hours

45mg/kg/day every 12 hours


40mg/kg/day every 8 hours

3. Urinary tract infection

Mild/Moderate infection doseSevere infection
Children ≥ 40kg500mg twice daily


250mg thrice daily

875mg twice daily


250mg thrice daily

Children > 3 months and less than 40kg25mg/kg/day in divided doses every 12 hours


20mg/kg/day in divided doses every 8 hours

45mg/kg/day in divided doses every 12 hours


40mg/kg/day in divided doses every 8 hours

4. Lyme disease (11)

By weightMild/Moderate infection doseSevere infection
Children ≥ 40kg500mg to 1g every 8 hours (up to max 4g/day) in divided doses for 14 days500mg to 2g every 8 hours (up to max 6g/day) in divided doses for 10-30 days
Children < 40kg25 to 50mg/kg/day in three divided doses for 10 to 21 days.100mg/kg/day in three divided doses for 10 to 30 days.

5. Community acquired pneumonia (12)

By weightDose
Children ≥ 40kg and more than 5 years500mg to 1g in every 8 hours
Children < 40kg aged two months to 5 years20 to 90mg/kg/day in divided doses

Amoxicillin clavulanate potassium combination is used in the lowest dose to bring down the adverse gastrointestinal drug effects. It is available in the form of suspension, chewable tablet, and tablet. The clavulanic acid in amoxicillin and clavulanate potassium formulation prevents amoxicillin degradation by β-lactamase enzymes. This extends the antibiotic spectrum of amoxicillin to many bacteria that are normally resistant to the drug (13).


  • The average dosage is 30mg/ kg of the child’s weight/ day.
  • Children above three months of age weighing up to 40kg – 25-45mg/kg/day, divided and given every 12 hours. For this age group usually, a suspension or chewable tablet is prescribed due to the clavulanic acid component.
  • Children weighing more than 40kg – 500-875mg, divided and given every 12 hours. Usually, a tablet is prescribed.

Once the child starts taking medicine, she should be feeling better by the second day.

The above dosages are a broad standard and they may or may not be suitable for all children.

[ Read: Prednisone For Kids ]

Note: If your child vomits within 30 minutes of taking medicine, then give the same dose again. You don’t have to repeat the dose if she vomits after 30 minutes.

What If You Missed A Dose Or Gave An Overdose?

If your child misses an amoxicillin dose of the course, give it as early as you remember. But, if you remember just before the time for the next dose, then leave out the missed one and continue with the regular schedule.

An overdose of amoxicillin may cause allergic reactions. A mild overdose does not pose any serious problems. However, an excess amount could damage your child’s kidneys, and lead to behavioral changes, confusion, severe skin rashes, pain in lower back, nausea, and less urination. In such cases, take them to the doctor immediately.

How Can An Overdose Of Amoxicillin Be Treated?

In a case of amoxicillin overdose, the doctor may prescribe some other medicines to control the side effects, or insert a tube into the stomach to pump out the excess dose. Some supportive treatments involve diuretic medications to prevent damage to the kidney and provide fluids through an intravenous line.

Treatment would depend on the extent of the effect on your child.

It is not just the overdose sometimes a normal amoxicillin dosecould also have an adverse effect.

Amoxicillin Side-effects In Children:

While taking amoxicillin, your child may experience certain discomforts. Consult your doctor if she exhibits any of the following symptoms (14):

  • Vomiting, diarrhea, or stomach pain. In case of vomiting and nausea, you may try giving the medicine after meals
  • Diarrhea gets severe and watery, contains blood or continues for more than four days
  • White patches inside your child’s mouth and throat
  • Soreness or itching around the vagina, in the case of girls
  • Breathing or wheezing problems
  • Blistering, redness, peeling of skin, yellowing of skin or eyes
  • Some allergic reactions such as hives, skin rashes, itching or swelling of lips, face, and tongue
  • Unusual bleeding or bruising
  • Fatigue and weakness
  • Heavy menstrual flow in girls
  • Loss of appetite
  • Decreased urination
  • Burning sensation or pain while urinating

Some of the side effects are temporary. Once the body adjusts to the medicine, the symptoms will go away and do not need any medical assistance. However, take your child to the doctor to avoid any severe health issues.

Amoxicillin For Kids: Important Points To Remember

  1. It is necessary to complete the course of the antibiotic. If it is discontinued, the bacteria might multiply, thereby leading to the onset of infection again.
  2. Store the medicine in cool temperature after you mix it.
  3. If your child has vomiting or diarrhea, then make them drink more water or any other fluid to replenish the loss.
  4. Do not give any medication for diarrhea unless it has been prescribed by your doctor.
  5. Give the amoxicillin dose at a fixed time every day and in the right amount.
  6. Your child’s teeth may look yellow or brown or might get gray stains. In such case, visit a dentist and get their teeth cleaned up.
  7. Give the medicine only to the child for whom it has been prescribed. It should not be shared with other children, even if they have similar symptoms.
  8. Unless your doctor recommends, children should not be given medicines containing ibuprofen or paracetamol along with this antibiotic.
  9. If your child has diabetes, then amoxicillin may interfere with the glucose tests giving false results. In such case, you must ask the doctor for alternative sugar tests.

[ Read: Bacterial Infections In Children ]

Although antibiotics are indicated to terminate the bacterial infections from the root, you need to be careful while giving amoxicillin to your children. Follow your doctor’s instructions carefully. Watch out for any discomforts that your child may experience while taking amoxicillin and seek medical attention as soon as possible.

Have an experience to share? Tell us in the comment section.

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