11 Best Anti-Aging Hand Creams To Smoothen Skin In 2024, Approved

✔ Research-backed

Continuous exposure to environmental aggressors and chemical-based products such as soaps and detergents causes visible aging symptoms on our hands. Thus, using rejuvenating hand creams is necessary. The best anti-aging hand creams moisturize, hydrate, and smooth damaged skin. If your hands have dark patches, crepey skin, and wrinkles, take a look at our handpicked anti-aging hand creams and get soft, smooth hands.

Top Picks

In This Article

11 Best Anti-Aging Hand Creams To Smoothen Damaged Skin In 2024

1. Best Allergy-Tested:Medix 5.5 Retinol Cream with Ferulic Acid Anti-Sagging Treatment

Medix 5.5 Retinol Cream with Ferulic Acid Anti-Sagging Treatment Image: Medix

Medix Cream combines anti-aging ingredients with natural antioxidants. Vitamin A, also known as retinol, reduces the appearance of wrinkles and fine lines and fights the effects of the sun on the skin. It also has ferulic acid, shea butter, aloe vera, chamomile, and natural apple, sunflower, and rosemary extracts to assist in hydrating and moisturizing your skin, leaving it feeling soft and smooth. Take a look at this unbiased review video to learn more about the Medix 5.5 Retinol Cream, one of the best hydrating hand creams for wrinkles.

Product Dimensions: 2.8 x 2.2 x 7.2 inches | Weight: 15.04 Ounces


  • Vegan
  • Cruelty-free
  • Parabens-free
  • Allergy-tested


  • Might have a strong scent

protip_icon Did you know?
Applying lotions and creams containing retinol or glycolic acid before bedtime can help treat and prevent skin wrinkling on the hands (2).


Why We Think It's Worth Buying

More than 12,227 buyers on Amazon have said the product lives up to the hype.

2. Best Cruelty-Free:Advanced Clinicals Anti-aging Hyaluronic Acid Cream

Advanced Clinicals Hyaluronic Acid Instant Skin Hydrator Image: Advanced Clinicals Store

This anti-aging face cream from Advanced Clinicals comes in a spa-size bottle and is ideal for those looking for hand creams with hyaluronic acid. You can use it as a body moisturizer, day cream, or hand lotion. It is enhanced with Borage oil, squalene, hyaluronic acid, and vitamin E, which have regenerative powers that improve complexion, and aloe vera, which soothes dry skin. The cream also helps increase the skin’s water retention and reduces the appearance of wrinkles and fine lines, promoting timeless beauty. Here’s an in-depth review video of the product.

Product Dimensions: 3.5 x 3.5 x 5 inches | Weight: 1.05 Pounds


  • Paraben-free
  • Cruelty-free
  • Dermatologically tested
  • Visible results in single-use


  • May not be suitable for use in cold climates

Why We Think It's Worth Buying

The 60,147 reviews on Amazon indicate that this product has a loyal following.

3. Best For Sun Protection:Skincare L De L Cosmetics Retinol Anti-Aging Hand Cream

If you are looking for hand creams with retinol, then this anti-aging cream is a good choice. It helps protect the hands, skin, nails, and cuticles and gives you soft and smooth hands. It also helps reduce fine lines and evens out your skin tone. The vitamin-rich hydrating formula makes the hands soft and supple after usage because it’s formulated with key ingredients such as green tea, glycerin and vitamins A, C, and E.

Product Dimensions: 6 x 5 x 4 inches | Weight: 2.4 Ounces


  • Helps condition dry hands and nails
  • Non-greasy
  • Anti-wrinkle formula
  • Prevents sun damage
  • Clinically proven results


  • Might have a strong fragrance

Our Reviewer's Experience

"This hand cream showed decent results in softening and moisturizing, significantly improving the appearance of my skin. While I don't like its scent, its non-greasy formula and lasting effect made me stick to it."

protip_icon Quick tip
Apply hand cream immediately after handwashing to restore the moisture barrier and prevent drying.

Medix 5.5 Retinol Cream with Ferulic Acid Anti-Sagging Treatment
Best Allergy-Tested
Advanced Clinicals Anti-aging Hyaluronic Acid Cream
Best Cruelty-Free
Skincare L De L Cosmetics Retinol Anti-Aging Hand Cream
Best For Sun Protection
Dimensions 2.8 x 2.2 x 7.2 inches 3.5 x 3.5 x 5 inches 6 x 5 x 4 inches
Weight 15.04 Ounces 1.05 Pounds 2.4 Ounces

4. Best For Sensitive Skin:TreeActiv Crepey Skin Repair Treatment

The anti-wrinkle hand cream from TreeActiv is one of the best hand creams as it contains the goodness of hyaluronic acid that tightens, softens, and conditions crepe paper-like skin. This cream contains glycolic acid and shea butter to soften fine lines, wrinkles, and sunspots. It also contains manuka honey and pure vitamin E oil, which work as a stretch mark remover, and aloe vera and sunflower oil, which hydrate and refresh the skin without irritating it.

Skin Type: All


  • Improves firmness
  • Offers restorative care
  • Makes skin look supple
  • Suits sensitive skin
  • Top-notch ingredients


  • Thin consistency

Why We Think It's Worth Buying

It's no wonder that this quality product has earned over 2,923 positive reviews on Amazon.

5. Best Multi-Purpose:Nivea Q10 Plus Age Care Hand Cream

Nivea Q10 Plus Age Care Hand Cream Image: Nivea

The delicate skin of your hands requires as much love and care as the facial skin. So this three-in-one hand cream by Nivea would be an ideal choice for reducing the appearance of wrinkles and age-related spots. The hand cream with anti-aging properties contains key ingredients such as glycerin, shea butter, and coenzyme Q10 to nourish dull and dry looking skin. These potent ingredients hydrate, soothe, and protect your skin from sun damage and prevent the formation of dark spots and fine lines, making it one of the best anti-dark spot hand creams available online.

Item Weight: 3.84 ounces | Product Dimensions: 1.57 x 2.44 x 5.63 inches


  • Rich and creamy texture
  • Has antibacterial properties
  • Non-greasy formula
  • Ideal for dry skin


  • Some might find the smell strong
  • Might leave a slight residue

Our Reviewer's Experience

"I've tried numerous creams, but this one stands out for its hydrating formula that leaves my hands feeling youthful. I also like that it's lightweight with a subtle scent. It's pretty good for regular use."

6. Best Non-Greasy: Derma-E Anti-Aging Shea Hand And Cuticle Cream

Derma-E Rosehip And Almond Anti-Aging Shea Hand Cream Image: Derma E

The Derma-E anti-aging shea hand cream is formulated to protect and nourish the hands, leaving them looking healthy and smooth. It contains natural ingredients, such as rosehip and almond oil, making it suitable for all skin types. The cream comes with a brush applicator for easy application. Further, its lightweight, cruelty-free formula relieves, soothes, nourishes dry skin, and protects it against dryness.


  • Non-greasy formula
  • Free of parabens and BPA
  • Non-toxic formula
  • Dermatologist-tested


  • Some may not like the smell
  • Dries down a little too quickly

7. Best Soothing:No7 Protect & Perfect Intense Advanced Nourishing Hand Cream

No7 Protect & Perfect Intense Advanced Nourishing Hand Cream Image: No7

No7 Protect & Perfect Intense Advanced Nourishing Hand Cream is a unique blend of antioxidants and skin-loving vitamins that protects the skin. This anti-aging hand cream is infused with nourishing key ingredients and age-defying actives, such as Pro-Retinol, which helps make your skin supple, and Pro-Vitamin B5, which provides deep conditioning. Suitable for all skin types, this advanced anti-aging formula is clinically formulated and proven to reduce the appearance of fine lines and wrinkles to give you healthy-looking hands.

Product Dimensions: 1.6 x 2.1 x 5.2 inches | Weight: 3.68 Ounces


  • Contains antioxidants
  • Skin-firming hand cream
  • Can be used alone or as a makeup base
  • Proven to deliver visible results in two weeks
  • Nourishes and soothes skin


  • May cause breakouts for some
  • May not be suitable for dry skin

Our Reviewer's Experience

"This hand cream's nourishing benefits have helped restore my skin's softness. Its non-greasy formula is a plus. Moreover, it has a gentle scent that doesn't overpower my senses. Overall, I am pleased with this product!"

8. Best For All Skin Types: ElemisPro-Radiance Anti-Aging Hand and Nail Cream

Elemis pro-radiance hand and nail cream provides deep conditioning for smoother, firmer, and younger-looking hands. This formula contains milk protein, camellia, avellana seed oil, virgin plum, omega 7, and macadamia, which create a protective layer on the skin and locks the moisture. It has a pleasant white flower fragrance.

Product Dimensions: 2.5 x 1.8 x 6.25 inches | Weight: 4.48 Ounces


  • Fast-absorbing
  • Suits all skin types
  • Non-greasy formula
  • Powerful active ingredients


  • Might not help fight age spots

Our Reviewer's Experience

"This hand cream smells wonderful! It's pretty moisturizing, so my hands feel nourished and soft. Moreover, consistent use has given me notable results while reducing wrinkles on my hands. I would recommend it!"

9. Best Antioxidant Properties:Retinol by Robanda Anti-Aging Hand Treatment

The retinol and Emblica-based anti-aging hand treatment cream brightens age spots, freckles, and hyperpigmentation, making it one of the best brightening hand creams. It contains retinol that helps reduce signs of aging and renews dead skin cells, and the hand cream with SPF for anti-aging protection also protects the skin from the sun’s harmful rays. The antioxidant properties of the cream can reduce the fine lines and wrinkles, making the skin soft, and the ingredients hydrate and moisturize the skin.

Package Dimensions ‏ : ‎ 5.24 x 2.09 x 1.3 inches; 7.05 Ounces


  • Cruelty-free
  • Paraben-free
  • Suits sensitive skin
  • Suitable for daily use


  • Smell may be too strong

Our Reviewer's Experience

"I found this cream's moisturizing capabilities noteworthy. It even helped reduce age spots with regular use. Also, its sun protection feature is a definite plus. It has been a cherished addition to my self-care routine!"

protip_icon Do remember
Applying a broad-spectrum, water-resistant sunscreen with SPF 30 or higher daily can help prevent wrinkly skin on hands.

10. Best For Daily Use:Crépe Erase Advanced Anti Aging Hand Repair Treatment

Crépe Erase contains patented TruFirm Complex, which supports the skin’s natural elastin production. This cream’s apple, dill, and sage extracts promote natural elastin production and structural resilience for a significantly firmer, smoother, and healthier appearance. Combined with the nine hydrators, it helps lock in moisture and relieves dry, dehydrated skin.

Product Dimensions: 2.3 x 1.5 x 5.85 inches | Weight: 3 Ounces


  • Suitable for daily use
  • Protects cuticles and nails
  • Makes the skin supple
  • Provides long-lasting moisture


  • Might take time to show results

Our Reviewer's Experience

"I've been using this product post-shower for a couple of months to maintain my skin's hydration. It is not a quick fix, although regular use has helped with dryness and fine lines. Also, I like that it does not have an overwhelming fragrance."

11. Best Hydrating:Onsen Anti Aging Hand Cream

If you are looking for an effective hand cream with shea butter for anti-aging benefits, the Onsen hand lotion can be a good choice. It is enriched with Japanese pagoda tree flowers, wasabi flavones, shea butter, and hyaluronic acid. It helps minimize irritation and redness, clarify skin flaws, and leave hands feeling smooth and hydrated. This anti-aging product is ideal for dry, cracked skin and is suitable for all skin types.The collagen-boosting hand cream protects the skin from oxidative stress caused by UV exposure and helps retain the skin’s moisture.

Package Dimensions ‏ : ‎ 6.81 x 3.82 x 1.77 inches; 5.6 Ounces


  • Paraben-free
  • Cruelty-free
  • Non-greasy
  • Eco- and bio-friendly


  • Has a strong fragrance

Our Reviewer's Experience

"I love this lotion for its moisturizing and skin-soothing benefits. A small amount goes a long way, quickly absorbing into my skin. While its scent is a bit strong for my preference, it's great for daily use."

*The prices provided in this article are based on the latest available information. However, they may vary due to changes in pricing by the seller and/or promotional offers.

How To Choose The Right Anti-aging Hand Cream?

Here are some important factors to consider when choosing the right anti-aging hand cream.

  1. Ingredients: Natural, vegan ingredients are ideal for use. Hyaluronic acid works well to hydrate the skin on the hands. You may also choose retinol-based nourishing hand creams for aging hands to boost collagen production, enhance suppleness, and balance out pigmentation. In addition, look for hand creams with peptides. Consider patch-testing the product before applying to ensure it is safe for your skin.
  1. Antioxidants: Anti-aging hand lotions and hand creams with antioxidants protect the hands from chemical and environmental aggressors. Also, hand creams with vitamin C can be useful due to their antioxidant properties, and often show exceptional results, such as improving skin texture.
  1. Harmful chemicals: Avoid parabens, phthalates, sulfates, and synthetic substances in cosmetics.
  1. Absorbency: Hand lotions that are light and quick to absorb help relieve chapped, cracked, and dry hands.

Gabrielle Richens, a London-based skin therapist and clean beauty blogger, says “Apart from using hand cream, I would advise you to use sunscreen and non-toxic hand wash. Moreover, always wear rubber gloves when doing the dishes.”

Frequently Asked Questions

1. Can a hand cream get rid of wrinkles?

If an anti-aging hand cream suits your skin type and contains anti-aging ingredients, such as retinol, along with certain other ingredients in particular ratios, the chances of minimizing the visible appearance of wrinkles could increase (1).

2. At what age do hands start looking old?

Depending on factors, such as the amount of UV exposure, cleansing agents you may use at home, the nature of your work, and genetics, your hands may be susceptible to premature aging anytime between your 20s and 30s.

3. How can I make my hands look younger?

Apart from protecting your hands from UV rays and harsh chemical-based cleansing agents, moisturizing them regularly, staying well hydrated, and using skin-friendly and anti-wrinkle hand creams may make your hands look younger.

Why Trust MomJunction?

Poulami Nag is a writer who reviews trending skincare and haircare products. She has put together this must-buy list of the best anti-aging hand creams after carefully researching and studying the consumers’ requirements and the safety of the products. She has also considered the available reviews from various trustworthy sources and chosen products that are trusted by customers to best suit your needs and preferences.

The Bottom Line

Your hands deserve just as much love as your face as you age. When you invest in a thoughtfully formulated anti-aging hand cream, you can keep your hands well hydrated and moisturized and prevent the formation of wrinkles and lines early on. And once you settle for the best anti-aging hand cream with ingredients such as vitamin E, collagen, and hyaluronic acid, your hands will transform to look healthy and supple. Thus, we have listed creams such as the vitamin-rich No7 Protect & Perfect Intense Advanced Nourishing Cream, the shea butter-infused Advanced Clinicals Anti-Aging Hyaluronic Acid Cream, and the nourishing Medix 5.5 Retinol Cream in this article. Also, keep in mind that it is of utmost importance that the hand cream you choose is free of chemical ingredients.

Infographic: Using An Anti-aging Hand Cream

Using anti-aging hand creams is an excellent way to achieve softer and hydrated hands. But that is not what their benefits are limited to. Learn more about the benefits of creams and their application procedure in this infographic.

Infographic: Using An Anti-aging Hand Cream

Illustration: Momjunction Design Team


MomJunction's articles are written after analyzing the research works of expert authors and institutions. Our references consist of resources established by authorities in their respective fields. You can learn more about the authenticity of the information we present in our editorial policy.
  1. Assessment of a Novel Anti-Aging Hand Cream
  2. What Can Make My Hands Look Younger?

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Gabrielle Richens

Gabrielle RichensSkin therapist

Gabrielle Richens is a London-based skin therapist with 20 years of experience. She is also a clean beauty blogger, and owner of The Rich Skin Club, an online anti-aging coaching service. She specializes in the education of skin, helping women to better understand the aging process, and build a knowledge in anti-aging skincare ingredients and how they work. She believes...read full bio