Dramamine For Kids: Safety, Side Effects And Precautions

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Dramamine is formulated from the generic drug dimenhydrinate and is useful for alleviating symptoms of motion sickness (kinetosis) such as nausea and vomiting. Dramamine for kids is usually available in chewable grape-flavored pills or tablets and is often used as an over-the-counter drug (1).

Dimenhydrinate, a first-generation drug, consists of diphenhydramine and 8-chlorotheophylline with antihistamine properties. The medicine works by reversing histamine’s effects that trigger the allergic reaction, leading to vomiting (2).

This post will help you understand the safety profile of Dramamine for kids.

Safety Of Dramamine For Children

Dramamine is considered safe for children aged two and above. It must not be used for children below two years unless prescribed by a pediatrician.You are advised to always consult a doctor before prescribing Dramamine to your child (3).

Dramamine Dosage For Children

Dramamine can be used to prevent an episode of motion sickness if your child takes a dose 30 minutes to one hour before travel. The recommended dosage is as follows (3).

Age (in years)DoseMaximum dose
2 to 5½ to 1 tablet every 6-8 hours.3 tablets in 24 hours or as directed by the doctor
6 to under 121 to 2 tablets every 6-8 hours6 tablets in 24 hours or as directed by a doctor

It is advisable to start with the lowest dose and increase it only if it does not work. Also, read the labels carefully before prescribing Dramamine to children.

Dramamine’s Mechanism Of Action

Uneasiness, nausea, and vomiting during traveling are the common symptoms of motion sickness. The brain maintains the body’s balance by analyzing signals from different body areas such as the eyes, inner ear (vestibule), intestine, and various motion-sensitive subcutaneous tissues (proprioceptors). Any mismatch can cause motion sickness.

Neurotransmitters such as acetylcholine, histamine, serotonin, glycine, and noradrenaline help forward mismatched signals to the vomiting center in the brain stem. Dimenhydrinate can block the central effects of both histamine and acetylcholine to act as an antiemetic (a drug that prevents vomiting). Additionally, it may prevent spasms in the gut by blocking the action of histamine on the intestinal muscles. However, the exact mechanism is unknown (4)(5).

Dramamine Side Effects In Children

As with most medications, Dramamine has side effects. The most common side effects in children include (4)

  • Drowsiness.
  • Dizziness.
  • Muscle weakness.

The less common ones include

  • Increased excitement.
  • Restlessness.
  • Dry mouth and nasal passages.
  • Blocked nose.
  • Blurry vision.
  • Increased heartbeat.

Consult your healthcare provider if any of these side effects become severe or your child experiences some other adverse effects.

Drug Interactions With Dramamine

Some drugs may cause unwanted or dangerous effects when administered with Dramamine. Talk to your doctor if your child is on the following medications (6)(7).

  • Anti-allergy or cold medications, such as diphenhydramine (Benadryl) or cetirizine (Zyrtec)
  • Antidepressants, such as sertraline (Zoloft)
  • Antianxiety drugs, such as fluoxetine (Prozac)
  • Antiepileptic drugs, such as valproate (Depakene)

These medications may depress the central nervous system and increase the severity of side effects encountered with Dramamine.

Precautions To Take When Using Dramamine

Dramamine is a non-prescription medication readily available in any pharmacy. However, take the following precautions when administering it to your child (3)(8).

  • Always consult your pediatrician before giving Dramamine if your child has breathing disorders, such as asthma or seizures.
  • Seek medical advice if your child has recently undergone any surgery, including dental surgery.
  • Ensure your child is not allergic to dimenhydrinate or any other inactive ingredient of Dramamine (aspartame, citric acid, magnesium stearate, methacrylic acid copolymer, sorbitol).
  • Do not use it if the blister pack has been tampered with. Store Dramamine at room temperature (20°C to 25°C).
  • Ensure the child chews the tablet before swallowing it.
  • The medication should be used under medical supervision if the child has phenylketonuria (an inherited condition that requires diet restrictions). Dramamine chewable tablets contain aspartame as a sweetener, which converts to phenylalanine.
  • Dramamine affects alertness in children. So, ensure they avoid activities such as cycling or skateboarding.
  • Consult with your pharmacist before giving any other OTC drug or any herbal preparation.
  • Keep Dramamine out of children’s reach.

Symptoms Of Dramamine Overdose

Children may accidentally overdose on Dramamine. In such a case, watch out for the following symptoms (6).

  • Dilated pupils
  • Seizures
  • Hallucination
  • Extreme drowsiness
  • Irritation and restlessness

Dramamine can alter the actions of many neurotransmitters and cause these effects. Seek emergency medical attention if you notice any of these symptoms in your child.

Frequently Asked Questions

1. Does Dramamine put children to sleep?

Dramamine is a brand name that has multiple products. Products containing Dimenhydrinate as the active ingredient may cause sleepiness as a side effect in children but are not meant to be used as sleeping aids. However, the ones having Meclizine as the active drug (usually labeled “less drowsy”) may show this side effect to a lesser extent (9).

2. Are Dramamine and Benadryl the same?

No, they are not the same. Benadryl contains the drug Diphenhydramine as the main active ingredient, whereas Dramamine contains Dimenhydrinate, which is a combination of two drugs (Diphenhydramine and 8-chlorotheophylline) (2) (10).

Dramamine or dimenhydrinate is a safe medication for motion sickness in children. However, ensure you consult a doctor before administering it to your child. Seek immediate medical help in case of severe side effects or overdose.

Key Pointers

  • Dramamine is a drug that alleviates the symptoms of motion sickness in children, and its dosage varies based on the child’s age.
  • Excess intake of Dramamine could cause muscle weakness, dizziness, and drowsiness.
  • Some drugs may cause unwanted reactions when administered along with Dramamine.
  • Consult a physician before giving Dramamine to your child to relieve motion sickness.


MomJunction's articles are written after analyzing the research works of expert authors and institutions. Our references consist of resources established by authorities in their respective fields. You can learn more about the authenticity of the information we present in our editorial policy.

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Dr. Joyani Das

Dr. Joyani Das did her post-graduation from Birla Institute of Technology, Mesra and PhD in Pharmacology. Previously, she worked as an associate professor, faculty of Pharmacology, for two years. With her research background in preclinical studies and a zeal for scientific writing, she joined MomJunction as a health writer. Her research work was published in international journals and publications, such... more

Dr. Dur Afshar Agha

Dr. Dur Afshar Agha is a consultant pediatrician with decades of experience in various medical facilities both in Pakistan and Saudi Arabia. She has headed the Department of Preventive Pediatrics at the prestigious, Children’s Hospital and Institute of Child Health in Pakistan and is a life member of the Pakistan Paediatric Association. She has also completed her Post Graduate Program... more