Hypotonia in Babies: Signs, Causes, Diagnosis & Treatment

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Hypo means less, and tone refers to the resistance of muscles in our bodies. So, the condition of hypotonia in babies refers to a reduced muscle tone, causing a flexed posture. However, it should not be confused with muscle weakness.

Hypotonia often occurs due to disorders of nerves, which control muscle movements. The condition commonly affects newborns and infants, although it may occur at a later age, as well. It is usually treated depending on the underlying cause, and prognosis and outcomes may vary accordingly.

This post discusses the signs, causes, diagnosis, and treatment of hypotonia in babies.

Signs And Symptoms Of Hypotonia In Babies

Babies with floppy baby syndrome can be like rag dolls without any muscle strength.

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Hypotonia may not be noticeable in babies younger than six months, although they might have it since birth. Babies with severe hypotonia (floppy baby syndrome) can be like rag dolls without any muscle strength. Many of them have a frog-like posture.

Hypotonic or floppy babies may have delayed motor development, but their intelligence is not affected by this condition. However, the clinical features may vary depending on the underlying causes of hypotonia.

The signs and symptoms of hypotonia in babies may include the following(1).

  • Floppy head due to no or less control on neck muscles even after three months of age
  • Arms or legs may slip through your hands while holding
  • Unable to keep any weight on shoulder or neck muscles
  • Weak cry
  • Arms and legs stay straight with no bending at joints, such as elbows, knees, or hips

Infants usually achieve head control after three months of life, but they have some muscle strength from birth. Motor developmental milestones such as crawling, sitting up, talking, eating, and walking, are often delayed in babies with hypotonia.

Causes Of Hypotonia

The most common cause of hypotonia is abnormalities in neurological control of muscle tone. Muscles need electrical signals from motor nerves for functioning. Any disruption in the signal generation or conduction may affect the muscle tone. Various inherited conditions and other factors can cause hypotonia.

Neurological disorders affecting the brain and spinal cord (central nervous system) may cause central hypotonia (2).

  • Cerebral palsy is a neurological condition causing problems with coordination and movement.
It is a neurological condition causing problems with coordination and movement.

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  • Meningitis is the infection of the outer membrane of the brain.
  • Injury of the brain and spinal cord.
  • Intracranial bleeding, which is bleeding inside the cranium.
  • Encephalitis is an infection of the brain.
  • Spinal muscular atrophy (SMA) is a genetic disorder affecting the muscle tone.

Neurological conditions affecting the peripheral nervous system (outside brain and spinal cord) may result in peripheral hypotonia (2).

  • Congenital myasthenia gravis is a condition that causes increased fatigue and weakness.
  • Muscular dystrophy may include a group of genetic conditions causing muscle weakness and disability.
  • Charcot-Marie-Tooth disease is a degenerative disease damaging the myelin that covers the nervous tissue. This may result in muscle weakness and other neurological issues.
  • Spinal muscular atrophy causes muscle weakness and gradual loss of movement.

Non-neurological conditions may also lead to hypotonia in some cases (2).

  • Premature birth, since muscle tone is not fully developed at the time of birth.
Premature birth may be responsible for hypotonia

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  • Down’s syndrome is a chromosomal anomaly causing physical and mental developmental delays.
  • Tay-Sachs disease is caused by mutation of genes on chromosomes producing specific proteins resulting in nervous system damage.
  • Prader-Willi syndrome caused by loss of function of some genes may also result in muscle weakness.
  • Connective tissue disorders, such as Marfansyndrome and Ehlers-Danlos syndrome, may also result in muscle weakness.
  • Autism and autism spectrum disorders may be associated with hypotonia in some babies.

Hypotonia can be a symptom of many diseases in babies. If there are no underlying causes, hypotonia usually improves when the baby grows older. However, some babies may have benign congenital hypotonia (BCH) present at birth without any underlying causes. BCH is non progressive hypotonia, which means it does not worsen with time.

Diagnosis Of Hypotonia

Pediatricians may refer your baby to a specialist (pediatric neurologist) if they suspect hypotonia after primary evaluation. Family history, medical history, pregnancy, and delivery-related issues are asked to identify the cause.

The following tests might be ordered to identify the cause of hypotonia in babies (3).

  • Blood tests and genetic testing help to determine various genetic disorders and other conditions.
Blood tests help diagnose genetic disorders in baby.

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  • CT scan helps visualize the nervous system damage.
  • MRI scan helps to visualize any abnormalities.
  • EEG or electroencephalogram records the electrical activity in the brain using electrodes. This may help to identify certain issues, such as seizures.
  • Nerve conduction studies (NCV) use electrodes over the skin to measure electrical signals transmitted from the brain or spinal cord to the muscles.
  • EMG or electromyography measures the electrical activity of the muscles.
  • Muscle biopsy helps to identify the structural abnormalities of the muscle tissue.

Treatment For Hypotonia In Babies

The choice of treatments may vary depending on the underlying cause. Hypotonia may not be curable if the underlying conditions are not curable. However, hypotonia due to certain causes, such as prematurity and infections, may cure once the baby grows out of these conditions.

Developmental pediatrician or pediatric neurologist may design a skill training program for your baby according to the requirements and age. The program may include the following therapies and procedures (4).

  • Physiotherapy may help to strengthen the muscles and improve coordination and posture.
Physical therapy can help babies with cerebral palsy

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  • Occupational therapy aims to teach day-to-day skills, such as feeding, or any other skills apt for the age. They also identify and provide training for feeding and swallowing They could also make recommendations for feeding support.
  • Speech and language therapy help the baby to learn speech and language skills relevant to their age.
  • Support equipment, such as a foot or ankle support, and mobility solutions, such as a wheelchair, are recommended depending on the baby’s age and severity of hypotonia.

Hypotonia in babies occurs when there is a disorder in the nerves controlling the muscle movements. As a result, you may notice floppy heads, sucking problems, and weak cries in these babies. Hypotonia may be caused by inherited conditions or other problems, such as injury, meningitis, muscular dystrophy, and premature birth. The condition in babies may remain the same, improve, or worsen over time. Hypotonia due to genetic and inherited conditions stay throughout life. Usually, the treatment depends on the cause of the hypotonia. If the cause is incurable, the condition persists. However, several therapies and management techniques help in improving the quality of life in children.

Frequently Asked Questions

1. How common is hypotonia in infants?

The exact incidence and prevalence of hypotonia are unknown as it may be a symptom of many other underlying conditions. Among congenital hypotonias, 60% of babies have central hypotonia. The rest of the cases are either from peripheral or unknown causes (5).

2. Is hypotonia a disability?

Hypotonia is a condition that can be counted as a disability since it affects a person’s independence to perform day-to-day activities (6).

3. Can hypotonia affect speech?

Hypotonia can affect the oral and facial muscles used to generate sounds. Therefore, children with hypotonia may experience speech problems (1).

Key Pointers

  • Hypotonia results in poor muscle tone mostly since birth but noticeable later.
  • Floppy hands and difficulty swallowing or sucking are signs of hypotonia in babies.
  • Hypotonia can be caused by cerebral palsy, encephalitis, or brain injury, among other reasons.
  • Support therapy or physiotherapy can help treat this condition.


MomJunction's articles are written after analyzing the research works of expert authors and institutions. Our references consist of resources established by authorities in their respective fields. You can learn more about the authenticity of the information we present in our editorial policy.
1. Muscle Weakness (Hypotonia); Boston Children’s Hospital
2. Causes; Hypotonia; National Health Service
3. Diagnosis; Hypotonia; National Health Service
4. Treatment; Hypotonia; National Health Service
5. Hypotonia; National Library Of Medicine
6. Hypotonia in Babies; Cleveland Clinic
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Dr Bisny T. Joseph

Dr. Bisny T. Joseph is a Georgian Board-certified physician. She has completed her professional graduate degree as a medical doctor from Tbilisi State Medical University, Georgia. She has 3+ years of experience in various sectors of medical affairs as a physician, medical reviewer, medical writer, health coach, and Q&A expert. Her interest in digital medical education and patient education made...
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Dr. Anuradha Bansal

Dr. Anuradha Bansal is a pediatrician and neonatologist working as assistant professor in the Department of Paediatrics at PIMS Jalandhar. She has done her MBBS and MD Pediatrics at GMCH, Chandigarh. Thereafter, she polished her skills as senior resident at MAMC, Delhi. She has also done IAP Fellowship in Neonatology at GMCH, Chandigarh and obtained the membership of the prestigious...
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