Can You Have Pepto Bismol When Breastfeeding?

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    Pepto-Bismol is commonly used to treat gastrointestinal ailments such as gastroesophageal reflux, nausea, bloating, upset stomach, belching, and diarrhea. However, some parents may wonder if it is safe to use Pepto-Bismol while breastfeeding.

    If you suffer from diarrhea or acidity while breastfeeding, dietary and lifestyle changes are recommended to resolve the problem. However, if these changes don’t alleviate the issue, you may consider taking Pepto-Bismol after consulting your doctor.

    Read this post to learn more about the ingredients of Peto-Bismol, if it is safe for nursing mothers, possible side effects, and alternative remedies while breastfeeding.

    What Is Pepto-Bismol?

    Pepto Bismol is an antacid used for relief from minor gastrointestinal ailments.

    Image: Shutterstock

    Pepto-Bismol is an over-the-counter (OTC) antacid used for relief from minor gastrointestinal ailments such as heartburn, nausea, upset stomach, bloated tummy, indigestion, gas, belching, and diarrhea(1). The medicine is available in liquid, capsule, and chewable tablet form.

    What Are The Ingredients Of Pepto-Bismol?

    The active ingredient of Pepto-Bismol is a compound called bismuth subsalicylate, which plays a significant role in alleviating symptoms of gastrointestinal problems. It forms a coat (protective layer) on the ulcers and helps in the secretion of prostaglandins and mucus that reduce the effects of stomach acid (2).

    The concentration of the compound varies based on the form of medicine. The manufacturer recommends no more than eight doses in 24 hours (3).

    Is It Safe To Have Pepto-Bismol When Breastfeeding?

    The US Centers for Disease Control and Prevention recommends lactating mothers avoid bismuth subsalicylate, as it can find its way into breast milk(4).

    The Journal of Travel Medicine also recommends lactating mothers avoid medication containing bismuth subsalicylate. Though the effects on the infant are unknown, salicylate was observed to be absorbed significantly (5).

    What Are The Side Effects Of Pepto-Bismol On Breastfeeding Baby?

    Metabolic acidosis as a side effect caused by maternal salicylate dosage

    Image: Shutterstock

    The side effects of Pepto-Bismol/Bismuth subsalicylate on the health of the infant are unknown.

    But there is some research on the impact of the compound salicylate, which is also called salicylic acid. Salicylate is found in Pepto-Bismol as well as in Aspirin, whose effects on the breastfeeding baby have been widely researched(6).

    Studies suggest that less than 1% of maternal salicylic acid dosage passes into breast milk(7). According to the Drug Principles in Lactation published by The American College of Clinical Pharmacy, “Salicylates should be avoided because of the risk of thrombocytopenia and tinnitus in a nursing infant (8).”

    The compound also holds the potential to cause the following side effects among breastfeeding infants:

    1. Metabolic acidosis: The American Academy of Pediatrics reports metabolic acidosis as a side effect caused by maternal salicylate dosage. Metabolic acidosis is a condition where the pH of the body fluids, including blood, decreases and causes excessive acidity. Acidosis quite commonly occurs due to a problem in the kidneys, which are responsible for maintaining the normal acidity of the body(9).

    Even though there are no studies to prove that the salicylates in Pepto-Bismol have the same side effects as that in Aspirin, it is safe to avoid it during breastfeeding, considering that salicylic acid can pass into breast milk.

    What Are The Alternatives To Pepto-Bismol?

    Increase fluid intake.

    Image: Shutterstock

    There are both medicinal and non-medicinal alternatives to Pepto-Bismol.

    1. Increased fluid intake, avoiding acidic foods, chewing ginger: Try avoiding acidic foods, chewing a piece of ginger or licorice. But, if your symptoms do not subside in a day, then consult a doctor and take the appropriate medication.
    1. Sodium bicarbonate and calcium carbonate-based antacids: You can consider antacids made with sodium bicarbonate (baking soda) to relieve acidity. These compounds have a localized effect within the stomach, and maternal dosage is seldom known to cause side effects in a breastfeeding baby (10).
    1. Simethicone: It provides relief from gas, fullness, and abdominal discomfort (11).Simethicone is considered relatively safe during breastfeeding as it is said to be unabsorbable from the maternal gastrointestinal tract. Even if it is absorbed, minute amounts are found in the breast milk. But, consult your doctor before taking Simethicone.
    1. Loperamide: The compound is used for controlling diarrhea, including traveler’s diarrhea (12). Studies found that loperamide is secreted in extremely small amounts in breast milk. Hence, the American Academy of Pediatrics considers loperamide compatible with breastfeeding (5). However, you should consult a doctor before using the medicine because you may have to monitor the baby for drowsiness, dry mouth, vomiting, and constipation.
    1. Histamine-based medicines: Theyare used to suppress acid secretion during GER and provide relief (13). Among the various histamine-based drugs, Famotidine has been found to be least secreted into breast milk (14) but it might alter the taste of the milk.
    1. Proton-pump inhibitors: This class of medicines, including esomeprazole and omeprazole (15)(16), help regulate the production of acid by the stomach to prevent acidity. A low, regulated dosage of these medicines is unlikely to cause any side effects in the breastfeeding baby(17).

    Pepto-Bismol, while breastfeeding, is usually not recommended as the bismuth salicylate contained in it may be secreted in breast milk and reach the baby. It is a medication for treating mild gastrointestinal disturbances whose effects on breastfeeding infants are not clearly known. However, the medication holds a theoretical risk of causing conditions such as thrombocytopenia, tinnitus, or metabolic acidosis in them. Try addressing minor digestive issues with home remedies first, and in case the condition is not relieved, check with your doctor for safer alternatives when lactating.

    Infographic: Who Should Not Take Pepto Bismol?

    Pepto Bismol is usually not recommended during breastfeeding due to the risk of the infant being exposed to salicylate. However, other underlying health conditions make Pepto Bismol unsuitable for use, too. The infographic below summarizes who should not take the medication.

    who should not take pepto bismol [infographic]
    Illustration: MomJunction Design Team

    Did you have to take Pepto-Bismol while breastfeeding? Tell us about your experience in the comment section below. 

    This post is for informational purposes only and is not a replacement for a doctor’s consultation. Do not use any medication without talking to your doctor.


    MomJunction's articles are written after analyzing the research works of expert authors and institutions. Our references consist of resources established by authorities in their respective fields. You can learn more about the authenticity of the information we present in our editorial policy.
    1. Pepto-bismol- bismuth subsalicylate; The Procter & Gamble Manufacturing Company
    2. Bismuth subsalicylate; Medical Pharmacology; Tulane School of Medicine
    3. Pepto-bismol FAQs; Pepto-Bismol Official Website
    4. Food-borne and waterborne illness; Centers for Disease Control and Prevention
    5. Lin H. Chen,; Breastfeeding travellers: precautions and recommendations; Journal of Travel Medicine (2010)
    6. Aspirin; Drugs and Lactation Database; NCBI
    7. Bismuth subsalicylate; Drugs and Lactation Database; NCBI
    8. Julie J. Kelsey, Pharm.D; Drug principles in lactation; Pharmacotherapy Self-Assessment Program 2016-2018; Ameircan College of Clinical Pharmacy
    13. Metabolic acidosis; Medical Encyclopedia; U.S National Library of Medicine
    14. Philip O. Anderson; Treating gastroesophageal reflux and heartburn while breastfeeding; Breastfeeding Medicine; Mary Ann Liebert Inc. Publishers
    15. A Young Seo, Nayoung Kim, and Dong Hyun Oh; Abdominal bloating: Pathophysiology and treatment; Journal of Neurogastroenterology and Motility
    16. Loperamide; Medline Plus; U.S National Library of Medicine
    17. H2 Blockers; International Foundation for Gastrointestinal Disorders
    18. Esomeprazole; Medline Plus; U.S National Library of Medicine
    19. Omeprazole; Medline Plus; U.S National Library of Medicine
    20. Esomeprazole; Toxnet Toxicology Network; U.S National Library of Medicine


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    shreeja pillai

    Shreeja holds a postgraduate degree in Chemistry and diploma in Drug Regulatory Affairs from the University of Mumbai. Before joining MomJunction, she worked as a research analyst with a leading multinational pharmaceutical company. Her interest in the field of medical research has developed her passion for writing research-based articles. As a writer, she aims at providing informative articles on health...
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    Melissa Kotlen

    (BSN, RN, IBCLC)
    Melissa Kotlen has been advising mothers on breastfeeding issues for 17 years. She is an International Board Certified Lactation Consultant (IBCLC) and a Registered Nurse (RN), with additional background in Midwifery. Melissa also provides lactation guidance and assists with business development matters for MommaWork, a company focusing on supporting working mothers. Melissa assists women on breastfeeding issues in private, classroom,...
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