Illustration: MomJunction Design Team
| Name | Gender | Meaning | |
|---|---|---|---|
 Sophina |  |  Girl | A little wise one |
| Sophocles | |  Boy | A man who is clever |
| Sophonisba | | Girl | A Carthaginian noblewoman; Sheltered by Ba'al |
| Sophronia | | Boy | One with a prudent and just mind |
| Sophy | | Girl | Wise, clever, and knowledgeable |
| Sopio | | Girl | Georgian form of Sophia; Wisdom |
| Soppa | | Boy | A woman with knowledge or wisdom |
| Sorana | | Girl | Sister |
| Sorcha | | Girl | Bright; Radiant |
| Soreana | | Girl | Strict and stern |
| Soredamors | | Girl | Name of Gawain's sister |
| Soreena | | Girl | A form of the Romanian name Sorina; Strict or stern |
| Sorella | | Girl | A sisterly woman |
| Soren | | Boy | Stern; Severe |
| Sorena | | Girl | A stern person |
| Soriandes | | Boy | An individual who is creative and versatile |
| Sorin | | Boy | He is like the Sun |
| Sorina | | Girl | A Sun-like woman |
| Sorinah | | Girl | A variation of Sorina; Strict or stern |
| Sorishu | | Boy | Hope of Jesus |
| Sorley | | Boy | He is a summer sailor |
| Sornegruex | | Boy | Enduring, happy, and from the bright stream |
| Sorrell | | Boy | A man with reddish-brown hair |
| Sorren | |  Unisex | Bright; Sun-like; Stern |
| Sorscha | | Girl | Free; Bright |
| Sorsha | | Girl | She is a woman who shines brightly |
| Sosa | | Unisex | Willow tree |
| Sosanna | | Girl | She is like a Lily flower |
| Soso | | Boy | He will add |
| Sosthenes | | Boy | One who has safe strength |
| Sostratos | | Boy | The safe army |
| Sotera | | Girl | Savior or deliverer |
| Sotiria | | Girl | She who brings salvation to people |
| Sotiris | | Boy | He is salvation |
| Soto | | Boy | He who is a forest grove |
| Sousanna | | Girl | A woman graceful like a lily flower |
| Southern | | Boy | From the south |
| Southwell | | Boy | One who comes from the spring in the south |
| Souzan | | Girl | She has the grace of a lily flower |
| Souzanna | | Girl | One who is noble like a lily flower |
| Sovia | | Girl | One with great wisdom and skills |
| Sowena | | Girl | Success or achievement |
| Spade | | Unisex | A word name; One who has a spade; A tool |
| Spakeman | | Boy | A man who speaks well and a lot |
| Spalding | | Boy | He who is from the split meadow |
| Spangler | | Boy | He is a tinsmith |
| Spark | | Boy | Happy |
| Sparke | | Boy | One who is gallant; One who has good manners |
| Sparks | | Boy | A vivacious, lively man |
| Sparrow | | Unisex | Small bird; Flutterrer |
| Spartak | | Boy | Georgian form of Spartacus; From the city of Sparta |
| Spas | | Boy | Derived from the Bulgarian word spasen meaning saved |
| Spasenka | | Girl | Rescue or save |
| Spaulding | | Boy | One whose home is in the Divided Valley |
| Spear | | Boy | Spear carrier |
| Speare | | Boy | A soldier who fought with a spear |
| Spearman | | Boy | A warrior who carries a spear |
| Spears | | Boy | Son of Spear; Son of a man who fights with a spear |
| Sped | | Boy | One who achieves success in life |
| Speed | | Boy | A very fast man |
| Speer | | Boy | A guard who carries a spear |
| Speers | | Boy | A son of the guard with a spear |
| Spelding | | Boy | A man who comes from the divided meadow |
| Spellman | | Boy | A man who can spell; A clerk or a writer |
| Spence | | Boy | A short form of spencer |
| Spencer | | Unisex | Dispenser of provisions |
| Spengler | | Boy | An occupational name, one who is a tinsmith |
| Spense | | Boy | One who proved to people |
| Spenser | | Boy | A provider; A dispenser |
| Speranza | | Girl | A woman who brings hope to men |
| Spere | | Boy | He who fights with a spear |
| Sperling | | Boy | The people who fought with spears |
| Spicer | | Boy | One who is a seller of spices |
| Spiers | | Boy | The son of Spier; A son of one who fights with the spear |
| Spike | | Boy | Ear of grain; Long nail |
| Spiridon | | Boy | A derivative of Spyridon, meaning spirit |
| Spirit | | Girl | Virtue |
| Spiro | | Boy | One who makes baskets |
| Spiros | | Boy | Basket-maker |
| Splanna | | Girl | Cornish word meaning brighter |
| Splendora | | Girl | A brilliant, bright woman |
| Spomenka | | Girl | Croatian name for forget-me-not flower |
| Sprague | | Boy | A lively, alert person |
| Sprig | | Girl | One who is like a spring |
| Spring | | Girl | To leap; To jump; To burst forth |
| Springer | | Boy | A man who jumps, leaps |
| Sprot | | Boy | A small man; An elf |
| Sprota | | Girl | An elf woman |
| Sproul | | Boy | An active, energetic person |
| Sproule | | Boy | One who is small, An elf |
| Sprow | | Boy | One who is an active person |
| Sprowle | | Boy | A person with a small stature; A short man |
| Spurgeon | | Boy | A medical plant used for healing |
| Spurrier | | Boy | A person who makes spurs; A spur-maker |
| Spyridon | | Boy | A big, round basket |
| Spyrling | | Boy | A little man who fights with a spear |
| Squandro | | Boy | A military unit that consists of soldiers, ships, and aircraft |
| Squier | | Boy | One who is a shieldbearer |
| Squire | | Boy | He who is a squire |
| Srecko | | Boy | Luck; A lucky and fortunate man |
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